The narrative begins with Captain Robert Walton's arctic expedition discovering the exhausted Victor Frankenstein stranded on the ice, desperate to tell his cautionary tale. Victor recounts his idyllic youth in Geneva alongside his adopted sister Elizabeth Lavenza and closest friend Henry Clerval, shadowed only by an intense intellectual curiosity. Consumed by natural philosophy at the University of Ingolstadt, Victor unlocks the secret of generating life and secretly constructs a giant eight-foot-tall being from stolen anatomical parts. Upon bringing the creature to life, however, Victor is immediately overcome by horror at its hideous appearance and flees his laboratory in terror.
When he returns, the creature has vanished, leaving Victor to descend into a debilitating nervous fever nursed only by the devoted Clerval. Months later, heartbreaking news summons Victor home: his youngest brother William has been brutally murdered, and a family servant, Justine Moritz, has been falsely accused, condemned by circumstantial evidence including a stolen miniature, and ultimately executed. Stricken by profound guilt, Victor realizes his creation committed the murder, yet remains silent out of fear that his unbelievable story will be dismissed as madness.
Seeking solace in the Alpine valleys, Victor confronts the creature face-to-face. The intelligent and eloquent being demands to be heard, recounting his lonely early months hiding near a secluded cottage where he secretly observed the impoverished De Lacey family, learning language, reading classical literature, and longing for human affection. When the creature finally revealed himself to the blind patriarch, the younger family members reacted with violence and terror, driving him away and cementing his path toward vengeance. Now, the creature confronts his creator with an ultimatum: Victor must fashion a female companion to end the creature's agonizing solitude, or face a relentless campaign of destruction against everyone Victor loves.
Initially refusing, Victor is eventually moved by the creature's arguments and travels to the remote Orkney Islands to secretly construct a second being. On the brink of completion, plagued by terrifying visions of a proliferating race of monsters, Victor destroys the unfinished female in front of the watching creature, who vows a final, chilling retribution before disappearing: 'I will be with you on your wedding-night.' Shortly after disposing of the remains, Victor drifts ashore in Ireland, where he is immediately arrested for the murder of Henry Clerval, whose body bears the signature black fingermarks of the monster.
Following months of agonizing imprisonment and a severe fever, Victor is acquitted with the aid of the benevolent magistrate Mr. Kirwin and returns to Geneva with his grieving father. Determined to protect his remaining loved ones and destroy his nemesis once and for all, Victor consents to an immediate marriage with Elizabeth, hoping to secure their happiness while secretly preparing for the ultimate, fatal confrontation with the creature he brought into the world.