The narrative opens with an intriguing historical discovery in an English meadow, where Dr. Thorndyke and his companions uncover the skeletal remains of a century-old gambler buried alongside a chest of ill-gotten treasure. Using an ancient Egyptian scarab and a mastery of compass variations, Thorndyke deciphers a hidden cipher to locate the long-lost loot while simultaneously exposing a modern thief. The story shifts to a seaside boarding house where a mysterious death occurs.
Through careful examination of room details, physical traces, and medical phenomena like rare tropical diseases, Thorndyke and his associates untangle a web of jealousy, mistaken identity, and murder. Later, the volume delves into other perplexing cases involving lost wills, missing diamonds, and suspicious deaths, each resolved through the methodical collection of physical evidence and scientific reasoning. Thorndyke's methodical application of forensic techniques consistently turns seemingly impossible puzzles into clear, logical solutions, vindicating the innocent and confounding criminals.