The narrative opens in a fragrant London studio where the artist Basil Hallward is finishing a magnificent portrait of Dorian Gray, a youth of extraordinary physical beauty. Observing the sitting is Lord Henry Wotton, whose cynical philosophy captivates Dorian, teaching him that youth and sensual experience are the only things in life worth pursuing. Confronted with the canvas that captures his transient perfection, Dorian utters a fateful wish: that he might remain forever young while the portrait bears the marks of age and sin.
Propelled by Lord Henry's hedonistic doctrines, Dorian plunges into a life of secret debauchery and aesthetic experimentation. He falls passionately in love with a young actress, Sibyl Vane, but cruelly rejects her when a disastrous performance shatters his idealized illusion of her art. Heartbroken, Sibyl commits suicide. Returning home, Dorian notices the first sinister change in Basil's portrait; the painted face now bears a subtle, cruel sneer. Horrified by this supernatural reflection of his inner corruption, he resolves to hide the canvas away in a locked room at the top of his house.
Over the ensuing years, Dorian remains physically untouched by time, maintaining an angelic facade that disarms suspicion while rumors of his depravity multiply. Basil Hallward confronts him about his infamous reputation and begs to see the soul behind the youth. In a fit of madness, Dorian shows him the hideously transformed portrait. Overwhelmed with horror, Basil urges him to repent, prompting Dorian to murder the artist in a blind rage and conceal the body using a chemist he blackmails into compliance.
Tormented by the memory of his crimes and the ever-worsening deformity of the canvas, Dorian attempts a brief redemption by sparing a village girl from his usual manipulation. Finding that the portrait has only grown more hypocritical and cruel, he realizes his supposed good deed was merely driven by vanity. Desperate to purge his conscience and destroy the last witness to his degradation, he takes the knife used to kill Basil and slashes the canvas.
The servants of the house are awakened by a piercing cry and a sudden crash. Upon forcing their way into the locked room, they find a magnificent portrait of their master restored to its pristine youth, while on the floor lies the corpse of an old man, withered, wrinkled, and loathsome of visage, identifiable only by the rings upon his dead fingers.